Born in Pistoia on 22 June 1684 into an established musical dynasty. He trained in Bologna under Giuseppe Torelli at the Basilica of San Petronio, absorbing the classical concerto grosso tradition before holding appointments in Ferrara and serving Prince Antoine I of Monaco as court maestro di cappella.
Dates verified on Treccani, DBI, vol. 68 (2007), voce "MANFREDINI, Francesco Onofrio" (https://www.treccani.it/enciclopedia/francesco-onofrio-manfredini_(Dizionario-Biografico)/); Georges Favre, Un prince mélomane au XVIIIe siècle: la vie musicale à la cour de Monaco, A. & J. Picard, Paris, 1976, pp. 31-45.
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